【Note】 This document has been translated from the Japanese original for reference purposes only. In the event of any discrepancy between this translated document and the Japanese original, the original shall prevail. The Company assumes no responsibility for this translation or for direct, indirect or any other forms of damages arising from the translation. <figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/38c6a241c07a4bf5848b3bedcec6e6a8/536.jpg" alt="" width="578" height="386"></figure> <figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/54900434748e4139b4e1c66b03bb1ecd/537.jpg" alt="" width="580" height="386"></figure> New York/February 23, 2021 MEDIROM Healthcare Technologies Inc. (NasdaqCM:MRM; Head office: Minato-ku, Tokyo; Representative Director: Kouji Eguchi; hereinafter referred to as the &apos;Company&apos;), today announces the opening of its latest relaxation salon, &apos;Spa Re.Ra.Ku,&apos; in Minami Kashiwa Natural Hot Spring SUMIRE, operated by Rakuya Co. (Head office:Chuo-ku, Tokyo; Representative Director: Uchida Shigeki) on February 11, 2021.  The Company operates 302 (as of January 31, 2021) relaxation salons across Japan centered around the Re.Ra.Ku™ brand. In 2017, the Company started opening salons in thermal bath facilities. Minami Kashiwa Natural Hot Spring SUMIRE is the 10th Spa Re.Ra.Ku to open (as of the end of January 2021).  The Company expects to continue to open new salons in thermal bath facilities through the ReRaKu brand. MEDIROM operates relaxation salons, running stations, and health guidance services that allow customers to have an intimate and honest view of their own body and health. Thermal facilities highlight body consciousness and contribute to increasing awareness and demand for our holistic health services.  The Company aims to provide customers who use Spa Re.Ra.Ku with an opportunity to address their health, and to support behavioral changes in their daily lives through Re.Ra.Ku.   The Company supports behavioral changes in daily life in order to lead customers to healthy lifestyles. As part of this effort, the Company operates relaxation salon centered around Re.Ra.Ku™, and provide healthcare services that combine treatments featuring Wing Stretch® with suggestions for alleviating &apos;mental&apos; and &apos;physical&apos; concerns. The practice of bathing at such spas has been shown to have additional salubrious effects, including raising body temperature and the expansion of peripheral nerves in the hands and feet, as well as promoting blood circulation. In Japan, a culture of &apos;going to Sento and Hot spring&apos; has taken root as a daily lifestyle habit since ancient times, and it has become a familiar health habit for the Japanese people. In addition to regular hot spring, various types of hot spring such as bedrock baths, lyly, relaxation services, resting areas, cafes, and other relaxing spaces are commonly available in thermal bath facilities. They are expected to be more than places just for bathing, but “leisure facilities” that provide physical and mental health. Currently, the market for thermal bath facilities in Japan is estimated to be worth around 280 billion yen per year (estimated 2018)*1.  According to Onsen Medical Science Research Center, “Association between the health indicators and bathing in Sento public bath” (2019.02), the most common expectation of Sento was &apos;health maintenance and promotion&apos; at 68.6%, and &apos;Relaxation and recovery from fatigue&apos; and &apos;health promotion, prevention of aging, and improvement of physical condition&apos; were the most popular responses. Bathing has a relaxing effect and is associated with relief of insomnia, shoulder and back fatigue, and promotion of good health. It is also a common understanding that bathing goes well with body care because bathing not only raises body temperature but also expands peripheral nerves in the hands and feet, and promotes blood circulation. Daily habits are essential for people to maintain, manage, and improve their health. It is said that lifestyle is deeply related to exercise, sleep, and meals. By providing body care after bathing through Spa Re.Ra.Ku, the Company will support customers to improve their lack of exercise and sleep.  *1 Source: Relaxation and Hot Spring Business Status and Outlook 2019 Edition, Yano Research Institute Ltd. About Spa Re.Ra.Ku<figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/fea972198dd542f7957181773cbbdc76/535.png" alt="" width="338" height="74"></figure> “Spa Re.Ra.Ku&apos; is a relaxation salon in thermal bath facilities, operated by Re.Ra.Ku, the largest relaxation salon brand by store count in Tokyo.*2 Customers are offered bodywork treatment featuring the Wing Stretch®, a method unique to Re.Ra.Ku, as well as esthetics, and acupuncture at Spa Re.Ra.Ku. A body-care service after bathing is expected to promote an even greater, synergistic relaxation effect. *2 Based upon an aggregate of store numbers provided by Digital Advantage Corp.    About Minami Kashiwa Natural Hot Spring SUMIRE<figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/0cdff6d9f9cf45c0bace65a01a3df058/538.png" alt="" width="256" height="256"></figure> <figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/a92abf746dc749aab938deee4ba50c65/677.png" alt="" width="304" height="204"></figure>Opening date: Thursday, February 11, 2021Opening hours: 7:00-24:00 Holidays: Third Thursday of March, June, September, and DecemberAccess: 10-minute walk from Minami Kashiwa Station on the JR Joban LineLocation : 1-272-8 Mukaikogane, Nagareyama-City, Chiba 270-0143, Japan Facility details・Four types of outdoor baths ・Five types of indoor baths ・Two types of saunas ・Bedrock bath space・A relaxation salon ・Eating and drinking area・Free rest area Forward-Looking Statements The information contained herein includes forward-looking statements. These statements relate to future events or to our future financial performance, and involve known and unknown risks, uncertainties and other factors that may cause our actual results, levels of activity, performance, or achievements to be materially different from any future results, levels of activity, performance or achievements expressed or implied by these forward-looking statements. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors which are, in some cases, beyond our control and which could, and likely will, materially affect actual results, levels of activity, performance or achievements. Any forward-looking statement reflects our current views with respect to future events and is subject to these and other risks, uncertainties and assumptions relating to our operations, results of operations, growth strategy and liquidity. We assume no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these forward-looking statements, even if new information becomes available in the future. The safe harbor for forward-looking statements contained in the Securities Litigation Reform Act of 1995 (the “Act”) protects companies from liability for their forward-looking statements if they comply with the requirements of the Act.  About MEDIROM Healthcare Technologies Inc.<figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/41df30828a1c4ff59c2a47bc0ab51e89/539.png" alt="" width="312" height="152"></figure>MEDIROM operates 302 (as of January 31, 2021) relaxation salons across Japan centered around Re.Ra.Ku™, which aims to provide healthcare services. In 2015, MEDIROM entered the health tech business, and conducted specific health guidance and constitution improvement programs, On-demand training app &apos;Lav™&apos;. MEDIROM also entered the device business in 2020 and is developing a smart tracker &apos;MOTHER Tracker™&apos;. Currently, MEDIROM is continuing development work with the goal of commercializing the product. In the future, MEDIROM plans to expand the scope of our business to include data analysis based on the lifestyle data we have accumulated since our founding. URL: <a href="https://medirom.co.jp/en">https://medirom.co.jp/en</a>  Overview of MEDIROM Healthcare Technologies Inc.Company Name: MEDIROM Healthcare Technologies Inc.Headquarters: Tradepia Odaiba, 2-3-1 Daiba, Minato-ku, TokyoCEO/Founder: Kouji EguchiEstablishment: July 2000Business Area: Relaxation Salon Management, Related Franchise Business, Digital Health Promotion Business and Devices Business ContactsInvestor Relations Teamir@medirom.co.jp Public Relations Teampress@medirom.co.jp

MEDIROM Healthcare Technologies Inc., Expands Subsidiary Spa Re.Ra.Ku Into  Thermal Bath Facilities ～Opening of Spa Re.Ra.Ku at Minami Kashiwa Natural Hot Spring SUMIRE on February 11～

MEDIROM Healthcare Technologies Inc. (Head office: Minato-ku, Tokyo; Representative Director: Kouji Eguchi; hereinafter referred to as &apos;MEDIROM&apos;), which went public on Nasdaq on December 29, 2020, has developed a new relaxation service called &apos;Suguru Osako Running Body Care&apos; in collaboration with Suguru Osako, a professional runner and Japanese record holder in the men&apos;s marathon, to help people recover from fatigue caused by exercise and improve their sports performance.  MEDIROM supports anyone who wants to take up running and helps conquer fears of fatigue or injury. Through the “Suguru Osako Running Body Care” service, Medirom can help take care of all kinds of athletes from runners trying to achieve a sub-3 to marathoners aiming to complete a 10km and Ironman competitors who have to run, bike and swim. Osako has always believed that it is important to prioritize exercising and post workout recovery. MEDIROM has also thought that in addition to body care work 2~4 times a month, people should exercise on a regular basis and facilitate recovery of their body soon  after exercise. The principles of these two parties merged to develop &apos;Suguru Osako Running Body Care,&apos; a new relaxation treatment service aimed at recovering from fatigue caused by exercise and improving sports performance. Re.Ra.Ku PRO Running Takebashi Imperial Palace Store will open on January 13, 2021 in the Palace side Building (adjacent to Takebashi Station on the Tokyo Metro Tozai Line) on January 13, 2021 and be the first store to feature  the &apos;Suguru Osako Running Body Care&apos; service. The Palace side Building is located facing the outer perimeter of the Imperial Palace, a route considered to be one of the most famous running spots in Japan. Now, the new Re.Ra.Ku brand, which consists of running stations and body care, can be experienced at the Imperial Palace, the sacred place for running. The actual &apos;Suguru Osako Running Body Care&apos; service is scheduled to start in February. 【Profile】 <figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/a9c385ac75c14d99ab2967c75a17cbed/548.jpg" alt="" width="250" height="375"><figcaption> </figcaption></figure>SUGURU OSAKO / Nike TeamDate of birth: Born on May 23, 1991 (age 29)Birthplace: Tokyo, JapanPersonal Bests5000m: 13:08.40 (Night of Athletics, July 2015) *national record10000m: 27:38.31 (Cardinal Invitational, April 2013)Marathon: 2:05:29 (Tokyo Marathon, March 2020) *national record   He began his track and field career in junior high school and went on to Saku Chosei High School in Nagano Prefecture, a strong Ekiden school. In his second year of high school, he won the sectional prize in the final seventh section of the National High School Ekiden, contributing to the team&apos;s first victory. He then went on to Waseda University, where he won the sectional prize twice in the Hakone Ekiden, and was selected for the Japanese 10,000m team at the 2013 Moscow World Championships. After graduation, he joined the Nissin Foods Group and won the section prize in the first section of the New Year Ekiden on New Year&apos;s Day, 2015. After leaving the company in March 2015, he joined the Nike Oregon Project, which had been his training base for some time. He is still active as a professional runner. ■About &apos;Suguru Osako Running Body Care The &apos;Suguru Osako Running Body Care&apos; is the only system in Japan that combines Suguru Osako&apos;s daily care method with relaxation under the supervision of his trainer, Gomi. In sports activities, it is necessary not only to receive care, but also to create a situation where tendons, muscles, and bones can move easily. Body care while performing joint exercises can facilitate muscle activities that extend and contract during exercise and increase the range of motion of joints. It is recommended not only for those who exercise and seek to improve their running movements, but also for those who feel stiffness in the lower body on a daily basis.  ■ About Re.Ra.Ku PRO Running Takebashi Imperial Palace Store <figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/441d85d817dc47249fc828d6af2e1e50/549.png" alt="" width="453" height="255"><figcaption> </figcaption></figure> Re.Ra.Ku PRO Running Takebashi Imperial Palace Store - A running station directly connected to the Imperial Palace and the stationLocation : 1-1-1 Hitotsubashi, Chiyoda-ku, Tokyo 100-0003, Japan Palaceside Building 1FPhone number: 03-3214-2777Opening date: Wednesday, January 13, 2021Opening hours: 7:00-22:00 (on weekdays)                       8:00-18:00 (Saturday, Sunday and holidays)No holidays (except year-end and New Year holidays)  ■ About &apos;Re.Ra.Ku <figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/8209b1463b034b0eac0f1d189a1c02db/550.jpg" alt="" width="189" height="66"><figcaption> </figcaption></figure> “Re.Ra.Ku” is a relaxation salon operated by MEDIROM mainly in the Kanto area. By providing care and stretching methods based on &apos;Wing Stretch®,&apos; a method unique to Re.Ra.Ku, Re.Ra.Ku supports customers in becoming more aware of their own health in their daily lives outside of their visits. Through treatment and communication, Re.Ra.Ku will continue to provide services that &apos;make people healthy for life,&apos; which is its concept.  ■About &apos;Re.Ra.Ku PRORe.Ra.Ku PRO is Re.Ra.Ku&apos;s sports-oriented brand that provides exercise and body care in one package. By combining sports facilities with Re.Ra.Ku,  Re.Ra.Ku PRO can provide services for daily fatigue care as well as specialized post-sports care.  Also, by providing a place for &apos;exercise habits x community,&apos; Re.Ra.Ku PRO will support the creation of friends with the same goals and objectives. MEDIROM will launch this brand nationwide, and also actively back up activities such as marathons, triathlons, and walking events. About MEDIROM Healthcare Technologies Inc. <figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/37aac2ae743641ef8224c7292b8f23e7/551.png" alt="" width="189" height="77"><figcaption> </figcaption></figure> MEDIROM became the first Japanese company in 21 years to list directly on Nasdaq on December 29, 2020. MEDIROM operates 290 (as of December 31, 2020) relaxation salons across Japan centered around Re.Ra.Ku™, which aims to provide healthcare services.  In 2015, MEDIROM entered the health tech business, and conducted specific health guidance and constitution improvement programs, On-demand training app “Lav™”. MEDIROM also entered the device business in 2020, and is developing a smart tracker “MOTHER Tracker™”. In the future, MEDIROM plans to expand the scope of our business to include data analysis based on the lifestyle data we have accumulated since our founding.URL ： <a href="https://medirom.co.jp/en">https://medirom.co.jp/en</a>  Overview of MEDIROM Healthcare Technologies Inc.Company Name: MEDIROM Healthcare Technologies Inc.Headquarters: Tradepia Odaiba, 2-3-1 Daiba, Minato-ku, TokyoCEO/Founder: Kouji EguchiEstablishment: July 2000Paid-in Capital: JPY 1,303,008,037 (including reserves)Business Area: Relaxation Salon Management, Related Franchise Business, Digital Health Promotion Business and Devices Business  Contact【Contact details for inquiries】MEDIROM Healthcare Technologies Inc.Public Relations DepartmentTel: 81-(0)3-6721-7364Fax: 81-(0)3-6721-7365E-MAIL: press@medirom.co.jp

MEDIROM Healthcare Technologies Inc. and Suguru Osako have jointly developed 'Suguru Osako Running Body Care,' a body care salon catered to recreational and pro athletes. ~A new approach to recovery from daily fatigue: exercise habits~

NEW YORK, Dec. 28, 2020 -- MEDIROM Healthcare Technologies Inc. (NasdaqCM:MRM) (“MEDIROM”), the holistic healthcare company from Japan, announced the pricing of its initial public offering of 800,000 American Depositary Shares (ADSs) at a price of US$15.00 per ADS. Each ADS represents one common share of MEDIROM. The ADSs are expected to begin trading on the Nasdaq Capital Market on December 29, 2020, under the symbol “MRM.” Gross proceeds before deducting underwriting discounts and commissions and other offering expenses are expected to be US$12.0 million. The closing of the offering is expected to occur on December 31, 2020, subject to the satisfaction of customary closing conditions. In addition, the Company has granted the underwriters a 45-day option to purchase up to an additional 120,000 ADSs at the public offering price, less underwriting discounts and commissions to cover over-allotments, if any. Maxim Group LLC is acting as the sole book-running manager in connection with the offering. The Company intends to use the net proceeds from the offering for working capital and general corporate purposes, which may include investments, acquisition or strategic collaborations to expand its customer base as well as develop and market new services. The offering is being conducted pursuant to the Company&apos;s registration statement on Form F-1 (File Nos. 333-250762 and 333-251777) previously filed with and subsequently declared effective by the Securities and Exchange Commission (“SEC”). A prospectus relating to the offering will be filed with the SEC and will be available on the SEC&apos;s website at <a href="http://www.sec.gov/">http://www.sec.gov</a>. Electronic copies of the prospectus relating to this offering, when available, may be obtained from Maxim Group LLC, 405 Lexington Avenue, 2nd Floor, New York, NY 10174, at (212) 895-3745. This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of, any security in any state or other jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such state or other jurisdiction. ■About MEDIROM Healthcare Technologies Inc.<figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/37aac2ae743641ef8224c7292b8f23e7/551.png" alt="" width="189" height="77"><figcaption> </figcaption></figure>MEDIROM operates 289 (as of June 30, 2020) relaxation salons across Japan centered around Re.Ra.Ku™, which aims to provide healthcare services. In 2015, MEDIROM entered the health tech business, and conducted specific health guidance and constitution improvement programs, On-demand training app “Lav™”. MEDIROM also entered the device business in 2020, and is developing a smart tracker “MOTHER Tracker™”. Currently, MEDIROM is continuing development work with the goal of commercializing the product. In the future, MEDIROM plans to expand the scope of our business to include data analysis based on the lifestyle data we have accumulated since our founding. URL : <a href="https://medirom.co.jp/en">https://medirom.co.jp/en</a> ■Overview of MEDIROM Healthcare Technologies Inc.Company Name: MEDIROM Healthcare Technologies Inc.Headquarters: Tradepia Odaiba, 2-3-1 Daiba, Minato-ku, TokyoCEO/Founder: Kouji EguchiEstablishment: July 2000Paid-in Capital: JPY 1,303,008,037 (as of December 31, 2019)Business Area: Relaxation Salon Management, Related Franchise Business, Digital Health Promotion Business and Devices Business ■ContactsInvestor Relations Team<a href="mailto:ir@medirom.co.jp">ir@medirom.co.jp</a> Public Relations Team<a href="mailto:press@medirom.co.jp">press@medirom.co.jp</a>

MEDIROM Healthcare Technologies Inc. Announces Pricing of Upsized $12.0 Million Initial Public Offering and Listing on NASDAQ

Tokyo, JAPAN―MEDIROM Healthcare Technologies Inc. (“MEDIROM”), the healthcare company which runs branded relaxation salons in Japan, today announced it has publicly filed a registration statement on Form F-1 with the U.S. Securities and Exchange Commission (“SEC”) relating to a proposed initial public offering of its American Depositary Receipts which represent the common shares of the Company. The number of ADRs to be offered and the price range for the proposed offering have not yet been determined. MEDIROM has applied to list its ADR on Nasdaq Capital Market. Maxim Group LLC is acting as lead manager and representative of the underwriters for the offering.  The proposed offering will be made only by means of a prospectus. Once available, a copy of the preliminary prospectus related to the offering may be obtained at the SEC&apos;s website at http://www.sec.gov or from the offices of  Maxim Group LLC, Attention: Prospectus Department, 405 Lexington Ave Second Floor, New York, NY 10174, telephone: 1-212-895-3500, fax: 212-895-3860.A registration statement on Form F-1 relating to the proposed offering has been filed with the SEC but has not yet become effective. These securities may not be sold, nor may offers to buy be accepted, prior to the time the registration statement becomes effective. This press release does not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction. The offering is subject to market conditions, and there can be no assurance as to whether or when the offering may be completed, or as to the actual size or terms of the offering. ■About MEDIROM Healthcare Technologies Inc. <figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/37aac2ae743641ef8224c7292b8f23e7/551.png" alt="" width="189" height="77"><figcaption> </figcaption></figure>MEDIROM operates 291 (as of October 31, 2020) relaxation salons across Japan centered around Re.Ra.Ku brand, which aims to provide healthcare services. In 2015, MEDIROM entered the health tech business, and conducted the government-initiated Specific Health Guidance program, and constitution improvement programs, on-demand health monitoring smartphone application, &apos;Lav&apos;. MEDIROM also entered the device business in 2020, and succeeded in developing the world&apos;s first thermo tech self-charging smart tracker &apos;MOTHER Tracker&apos;. MEDIROM is planning to expand the scope of its business to include data analysis based on the lifestyle data it has accumulated since its founding.URL ： https://medirom.co.jp/ ■Overview of MEDIROMCompany name: MEDIROM Healthcare Technologies Inc.Headquarters: 2-3-1 Daiba, Minato-ku, Tokyo, JapanCEO/Founder: Kouji EguchiEstablishment: July 2000Business: Relaxation Salon Management, Related Franchise Business, Health Promotion Business and Wearable Devices Business ■Contact【Contact details for inquiries】MEDIROM Healthcare Technologies Inc.Investor Relations DepartmentE-MAIL: ir@medirom.co.jp

MEDIROM Healthcare Technologies Inc. Announces Filing of Registration Statement for Proposed Initial Public Offering on NASDAQ

“Acquired, lifestyle factors at root cause for many diseases.” Revorf Co., Ltd. and MEDIROM Healthcare Technologies Inc. are pleased to announce that they have entered into a business collaboration agreement as of September 1st, 2020. MEDIROM Healthcare Technologies Inc. (headquartered at: Minato-ku, Tokyo; Representative Director: Kouji Eguchi; hereinafter, “MEDIROM”), which operates 286 salons nationwide under Re.Ra.Ku™ brands and others, has more than 59,000 visits per month and a customer healthcare database of 1.4 million. In addition to basic attributes such as age, gender, and residential area of the customer, the healthcare database also has information on the customer&apos;s diet and exercise habits, causes of stress, smoking, drinking and other lifestyle factors. All information is accumulated in a secure databank that features analytics and prescriptive healthcare applications. Revorf Co., Ltd. (headquartered at: Chuo-ku, Tokyo; Representative Director: Shinichi Sueta; hereinafter, the “Revorf”), carries out genetic diagnostic development, drug discovery, and bio-related data analysis through the use of bioinformatics technology (focus on RNA analysis) and Revorf&apos;s proprietary technology. MEDIROM and Revorf have now agreed to collaborate to create a multifaceted data bank that reveals, seeks to prevent and address disease factors resulting from lifestyle choices. The companies leverage each other’s databases and technology to conduct joint research aimed at elucidating the relationship between individuals’ gene expression and their lifestyle. Currently, market prescriptions focus on curing already sick patients (ex-post) while preventative measures (ex-ante) remain under tapped, both commercially and intellectually. Researchers believe that only about 30% of the onset in major diseases can be attributed to congenital factors (DNA) while acquired factors (lifestyle) account for 70% of the total. RNA expression appears to be a core catalyst, affected by both congenital and acquired factors, in the expression of bodily abnormalities that ultimately lead to a state of disease. The two companies aim to identify the causes of acquired diseases through joint research and crystalize potential solutions through lifestyle modifications and therapy. <figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/b9cae230d7e94b5284b9ab43bf84f735/678.png" alt="" width="409" height="183"><figcaption> </figcaption></figure> The two companies envision the following specific methods for this joint research. STEP1: Hashing MEDIROM&apos;s Big Data on Lifestyle Habits In accordance with ethical and legal guidelines under Japan’s Personal Information Protection Act, MEDIROM accrues and analysis data collectively through its: relaxation salons, “Re.Ra.Ku™”, On-Demand Lifestyle Management App “Lav™”, and wearable technology featuring the world’s first body-heat generated electricity (self-charging) activity tracker “MOTHER Tracker™”. STEP2: Analyzing trends by matching hashed big data on lifestyle habits with RNA data using AI Data collected is hashed and in combination with Revorf’s bioinformatics technology, sequenced through machine learning AI and RNA analysis to identify lifestyle factor, disease clusters, and practical insights. STEP3: Identifying disease factors by matching RNA expression with lifestyle habits Identifying factors involved in the onset of Life Habits Disease and others. Clarifying the relationship between congenital factors (genes), acquired factors (lifestyle) and post-treatment (medication and surgery). [Our Aim for Healthy, Disease Free Future] Supporting behavioral changes in lifestyles at medical and other settings After the factors involved in lifestyle diseases have been identified, we can support the diagnosis and doctor&apos;s advice in the hospital accurately. In the field of insurance, it is possible to predict disease risk in advance and benefit customers with services such as premium incentives. Also, it allows for supporting positive behavior by advisors and presenting an increased risk of disease at offline stores that offer lifestyle-related services such as fitness gyms and relaxation salons and online from a tablet, smartphone or other device. It will enable you to give accurate advice on stretching and eating a balanced diet in your daily life. We can expect to see people&apos;s behavioral changes encouraged and a dramatic reduction in the number of patients suffering from lifestyle diseases with alerts at the stage of increased disease risk being made through all life related services. Why unravel lifestyle diseases? Background to the Business Alliance It is said that about 60% of diseases are caused by lifestyle-related diseases, and cancer, cerebrovascular disease and heart disease, the three leading causes of death in Japan, are generally a major cause of death from lifestyle-related diseases. Therefore, it is estimated that about 30% of healthcare costs are generated from lifestyle diseases. What are lifestyle-related diseases? The term refers to a group of diseases where eating habits, exercise habits, rest, smoking, drinking and other lifestyle habits are related to the development and progression. For example, the following diseases are considered to be included in the list.   Eating habits: Insulin-independent diabetes mellitus, Obesity, Hyperlipidemia (except familial), Hyperuricemia, Cardiovascular disease (except congenital), Colorectal cancer (except familial), Periodontal disease, etc.    Exercise habits: Insulin-independent diabetes mellitus, Obesity, Hyperlipidemia (except familial), Hyperuricemia, Hypertension, etc.   Smoking: Squamous cell carcinoma of the lung, Cardiovascular diseases (except congenital ones), Chronic bronchitis, Emphysema, Periodontal disease, etc. Drinking: Alcoholic liver disease, etc.  * Reference  Smart Life Project Secretariat (Health Division, Health Bureau, Ministry of Health, Labour and Welfare)  URL: <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https://www.smartlife.mhlw.go.jp/disease/&amp;esheet=52274633&amp;lan=en-US&amp;anchor=https://www.smartlife.mhlw.go.jp/disease/&amp;index=1&amp;md5=7b7e133d84c419b7d5e0503eecdedd50">https://www.smartlife.mhlw.go.jp/disease/ </a> The two companies believe that it is important to clarify the etiology of lifestyle diseases and to build a body that does not develop lifestyle diseases. MEDIROM and Revorf entered into a business alliance with the idea that their joint research would enable them to uncover the causes of lifestyle-related diseases and realize &apos;a disease-free society&apos;. About MEDIROM Healthcare Technologies Inc. <figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/d036a8aa511a4adf94645083a438374f/555.png" alt="" width="189" height="93"><figcaption> </figcaption></figure>MEDIROM operates 286 (as of July 31, 2020) relaxation salons across the country centered around Re.Ra.Ku™, which aims to provide healthcare services. In 2015, MEDIROM entered the health tech business, and conducted specific health guidance and constitution improvement programs, On-demand training app &apos;Lav™&apos;. MEDIROM also entered the device business in 2020, and succeeded in developing the world&apos;s first non-rechargeable smart tracker &apos;MOTHER Tracker™&apos;. In the future, we will expand the scope of our business to include data analysis based on the lifestyle data we have accumulated since our founding.  URL: <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https://medirom.co.jp/en&amp;esheet=52274633&amp;lan=en-US&amp;anchor=https://medirom.co.jp/en&amp;index=2&amp;md5=2f0eb3051f7549932d527de5a138f610">https://medirom.co.jp/en</a> Overview of MEDIROM Healthcare Technologies Inc. Company name: MEDIROM Healthcare Technologies Inc.  Headquarters: Tradepia Odaiba, 2-3-1 Daiba, Minato-ku, Tokyo  CEO/Founder: Kouji Eguchi  Establishment: July 2000  Business: Relaxation Salon Management, Related Franchise Business, Health Promotion Business and Devices Business About Revorf Co., Ltd. <figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/8318e829ac074e839b6f7880b2393e31/556.png" alt="" width="159" height="57"><figcaption> </figcaption></figure>Revorf is dedicated to making people around the world smile through using bioinformatics technologies such as machine learning, etc., detecting information that still lies in the human genome, creating superior diagnostics and therapeutics, and elucidating the pathological mechanisms.  URL: <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https://www.revorf.com&amp;esheet=52274633&amp;lan=en-US&amp;anchor=https://www.revorf.com&amp;index=3&amp;md5=91392ab954b416f0b389a7bce9aaa3e7">https://www.revorf.com </a> Overview of Revorf Co., Ltd. Company name: Revorf Co., Ltd.  Headquarters: Tosho Building 8F, 3-8-3 Nihonbashi-Honcho, Chuo-ku, Tokyo  CEO/Founder: Shinichi Sueta  Establishment: November 2019  Business: Genetic Diagnostics Development/Drug Discovery Support/Bio-Related Data Analysis Contacts[Contact details for inquiries]  MEDIROM Healthcare Technologies Inc.  Public Relations: Daimu Nakamura  Tel: 81-(0)3-6721-7364  Fax: 81-(0)3-6721-7365  E-MAIL: <a href="mailto:press@medirom.co.jp">press@medirom.co.jp</a> Revorf Co., Ltd. Shinichi Sueta Tel: 81-(0)3-6231-0433 E-MAIL: <a href="mailto:information@revorf.com">information@revorf.com </a>

Discovery of Disease Factors via Lifestyle DataBase x AI Gene Expression Analysis

MEDIROM, which operates over 300 salons nationwide under Re.Ra.Ku brands and others (Head office: Tokyo, Japan), is pleased to announce that it has received an order for the MOTHER wearable tracker from Kansai Medical University Hospital (Headquartered in Hirakata, Osaka, Japan). Wearable Tracker MOTHER About the MOTHER Wearable Tracker Since the product announcement at CES 2020, the world’s largest technology conference held in Las Vegas, MOTHER has received considerable domestic and international attention as a health and activity tracker for user management across fitness companies and for employee health management across private companies. MEDIROM has received numerous inquiries from the medical sector, including rehabilitation centers, medical institutions, pharmaceutical companies and nursing homes. And now we are pleased to announce that we have received a planned order from Kansai Medical University Hospital for our debut self-charging device MOTHER the first of its kind in the medical field. (Due to the impact of the global COVID-19 outbreak, stabilizing the production line has become an issue. For this reason, we have not set a delivery date and take provisional orders for the time being.） MOTHER is the world’s first activity tracker (wearable band) that uses body heat to generate electricity, through Thermoelectric technology, thus creating a perpetual self-charging machine and enabling the device to record user’s activity, sleep length and quality, calorie consumption and other biometrics without ever needing an external charge hub. In addition, to facilitate data extraction, gathering and analysis from the end users of the device, Mother’s SDK will be provided to 3rd party (partner companies). About SDK (Software Development Kit) We expect MOTHER to be a platform for health management. By providing the SDK, our healthcare service providers (partner companies) will be able to import MOTHER’s various end user data (activity, sleep, and calorie consumption) and leverage through their own apps without needing a separate dedicated (closed system) app. This will benefit both app users and service providers to utilize health data in a streamlined fashion. [About Kansai Medical University Hospital] Kansai Medical University is a comprehensive medical university. Founded in 1928, the university has a Faculty of Medicine, a Faculty of Nursing and a Faculty of Physical Therapy (scheduled to open in 2021). In January 2006, Kansai Medical University Hospital opened as a hospital with special functions and has now become one of the core hospitals known as “advanced treatment hospitals”. Kansai Medical University Hospital is also actively researching and clinically applying biometric sensors in the fields of disease management and telemedicine. [About MATRIX INDUSTRIES] MATRIX INDUSTRIES was established in 2011 as a Silicon Valley material science company by CEO Akram Boukai and CTO Douglas Tham. The team consists of doctoral graduates from California Institute of Technology, Massachusetts Institute of Technology, Harvard University, University of California San Diego, and veterans with over 25 years of advanced technology dissemination activities. It consists of development and production experts. [About MEDIROM Healthcare Technologies Inc.] MEDIROM’s mission is to help people lead healthier and happier lives with more vitality. Since 2000, MEDIROM has expanded its relaxation salon “<a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=http%3A%2F%2Freraku.jp%2F&amp;esheet=52235093&amp;lan=en-US&amp;anchor=Re.Ra.Ku&amp;index=1&amp;md5=e3d71183bec41a5b1d00c5fc905b43c7">Re.Ra.Ku</a>” to over 300 salons becoming the No. 1 franchise relaxation brand in the Tokyo Metropolis and the category leader in leveraging retail customer data to improve product advertising and marketing, and digital telehealth services. In 2015, MEDIROM established the Institute for Healthcare, and in collaboration with doctors and university professors, it has expanded its activities such as research on health promotion and disease prevention in non-disease field, and coordinated projects specialized in the healthcare field. [Overview of MEDIROM Healthcare Technologies Inc.] Company name: MEDIROM Healthcare Technologies Inc. Headquarters: Tradepia Odaiba 16F, 2-3-1 Daiba, Minato-ku, Tokyo CEO/Founder: Kouji Eguchi Establishment: July 2000 Paid-in Capital: JPY 1,303,008,037 (as of December 31, 2019) Business: Relaxation Salon Management, Related Franchise Business and Health Promotion Business URL: <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fmedirom.co.jp%2Fen%2F&amp;esheet=52235093&amp;lan=en-US&amp;anchor=https%3A%2F%2Fmedirom.co.jp%2Fen%2F&amp;index=2&amp;md5=2978c01e7e53cac9d5a0a81f2a9ed69f">https://medirom.co.jp/en/ </a> *MLA Documentation: “Japan Medical Market.” Pacific Bridge Medical, https://www.pacificbridgemedical.com/target-asian-markets/japan-medical-market/.

MEDIROM Announces Its First Order of MOTHER, World’s First Self Charging Activity Tracker, from a Medical Institution. Entry into $34 Billion Japanese Medical and Nursing Care Market*.

MEDIROM Healthcare Technologies Inc., which provides health management support services to customers under relaxation salon “Re.Ra.Ku” brands and others (headquartered at: Minato-ku, Tokyo; Representative Director:Kouji Eguchi, hereinafter &apos;MEDIROM) has started &apos;Seranabi&apos;, a job serach portal specialized in the relaxation industry, Seranabi aims to match existing therapists and new job seekers, including those with no experience, with a workplace where they can contribute meaningful work in helping others. MEDIROM will strive to solve the mismatch in the relaxation industry by providing job information that matches the needs of job seekers as well as broadening the options for working as a therapist through &apos;Seranabi&apos;. MEDIROM plans to gradually increase the number of job listings for job seekers to more than 300 branches across Japan, including group branches. 【About Seranabi】<figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/d042a590db9c492a8041e1a42ca95cbd/558.png" alt="" width="300" height="47"><figcaption> </figcaption></figure>URL：<a href="https://seranabi.jp/">https://seranabi.jp/</a> Feature 1: Specialized in Therapist Jobs Seranabi is an industry-specific recruiting media specializing in body care therapists and estheticians. Our recruiting advisers who have experience and skills as a therapist and are familiar with the market, will help each and every job seeker to find a job that matches his/her needs and a place where he/she can work comfortably as a therapist. Feature 2: Applying Is A Breeze! (1) Search by location and the type of work a job seeker wants to do.(2) Find the salon he/she wants to work.(3) Fill out the six items to apply. With these 3 easy steps application, an invitation to an information session for the store of each choice will be sent. No need to submit a resume or work schedule when applying, and if the conditions doesn&apos;t match up with the preferred store, MEDIROM will find one that best meets the requirements. In addition, MEDIROM operates a free training facility called &apos;Re.Ra.Ku College&apos;, so even if they lack therpaist experience, the beginners can learn the skills that they need and make a debut as a therapist. 【Background of the launch of Seranabi】Re.Ra.Ku, our relaxation salon brand, has been in operation for 20 years to promote health and prevent diseases through health management solutions. MEDIROM realizes that promoting employment in the relaxation industry and providing an environment where therapists can work with peace of mind are essential for stable and effective customer service. In addition to full-time therapists,  MEDIROM also welcomes housewives and people from various industries (e.g. food and beverage, theater, etc.) who want to work as therapists on the side. MEDIROM has developed &apos;Seranabi&apos; to help those who are interested in working as a therapist find a job easily, quickly and clearly. As the number of salons in the group expands, MEDIROM is now able to post jobs at more than 300 salons across Japan. This means that even if their lifestyle changes, such as marriage, childbirth, or moving due to a job transfer, people who want to continue to work as a therapist can do it in a safe and secure environment. 【Future Outlook】By the end of April 2020, MEDIROM will be expanding the recruitment area beyond the current Tokyo metropolitan area (Tokyo, Kanagawa, Chiba, Saitama, and Ibaraki prefectures) to include (Tochigi, Aichi, Osaka, Hyogo, and Fukuoka prefectures), where we have group salons. 【About MEDIROM Healthcare Technologies Inc.】 <figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/ad240e5750d44fcda4f8cd7decdd5b9a/560.png" alt="" width="300" height="129"><figcaption> </figcaption></figure>MEDIROM operates 288 (as of February 29, 2020) relaxation salons across the country centered around Re.Ra.Ku™, which aims to provide healthcare services. In 2015, MEDIROM entered the health tech business, and conducted specific health guidance and constitution improvement programs, On-demand training app “Lav™“.   [Overview of MEDIROM Healthcare Technologies Inc.]Company name: MEDIROM Healthcare Technologies Inc.Headquarters: Tradepia Odaiba, 2-3-1 Daiba, Minato-ku, TokyoCEO/Founder: Kouji EguchiEstablishment: July 2000Business: Relaxation Salon management business / Franchise business / Health tech business  [Contact details for inquiries]MEDIROM Healthcare Technologies Inc.Public Relations: Yamaki/NakamuraTel: 81-(0)3-6721-7364Fax: 81-(0)3-6721-7365E-MAIL: <a href="mailto:press@medirom.co.jp">press@medirom.co.jp</a>

MEDIROM Healthcare Technologies Inc. , operator of Re.Ra.Ku, opens 'Seranabi', a dedicated recruiting platform serving therapists and the Relaxation Industry.

MEDIROM is today announcing a partnership with MATRIX Industries enabling users in the US and Japan to monitor their health activities 24/7 by delivering the world’s first health monitoring smartband MOTHER that never requires charging. “MEDIROM operates 284 relaxation salons all over Japan and has helped millions of people to get a healthier life. And now we have developed an on-demand health monitoring app Lav under the supervision of doctors to create a platform that can prevent people from getting lifestyle-related diseases,” said MEDIROM CEO Kouji. “We have tried a lot of wearables to keep users monitoring their health, however, it didn’t last long.” As research shows, the number one reason consumers stop using wearables is because they take them off to charge and forget that they exist. By partnering with MATRIX, we hope to develop a smart-tracker that never requires charging and can provide accessible options for consumers. MATRIX has developed PowerWatch the world’s first smartwatch that never requires charging- by applying innovative technology like its Gemini TEG（Thermoelectric Generator）and Mercury Boost Converter that enables body heat to generate electricity. With PowerWatch, it is possible to measure calorie consumption, activity and sleep, without ever needing to stop and charge. [Best features of MOTHER] 1. The World’s First Health Monitoring Wearable that Never Requires Charging MOTHER is a smart-tracker that never requires charging and can provide accessible options for consumers. With MOTHER, we are particular about the unisex design that can be worn stylishly regardless of gender, and distinguish from other trackers on the market. 2. Releasing the SDK for Apps so that any healthcare service provider can get device tracking information the smarter ever With MOTHER, we will open up the SDK（Software Development Kit） for Apps to help any healthcare service provider to build and expand their own service easily. “You usually have to download two different Apps on your phone when you start using any healthcare service with smart-tracker because the data can not be directly synchronize to the App. Usually at first, you have to synchronize the data to the Original App of the device ,and then synchronize the data to another App that you mainly want to use to apply the tracking data. It’s also been a huge block for any healthcare service provider to expand their healthcare service,” said MEDIROM CEO Kouji. “Any company will be able to directly import MOTHER tracking data into their services. We believe that it can contribute to the development of any business that require user’s health information, such as nursing care, fitness gym operators and other health-related industries. ” Exhibition information CES®2020 Date: January 7 (Tue)-10 (Fri), 2020 Venue: Las Vegas, Nevada, USA Booth: The Venetian. Suite 36-307. WEB: <a href="https://www.ces.tech/">https://www.ces.tech/ </a> [About MATRIX INDUSTRIES] MATRIX INDUSTRIES was established in 2011 as a Silicon Valley material science company by CEO Akram Boukai and CTO Douglas Tham. The team consists of doctoral graduates from California Institute of Technology, Massachusetts Institute of Technology, Harvard University, University of California San Diego, and veterans with over 25 years of advanced technology dissemination activities. It consists of development and production experts. [About MEDIROM Healthcare Technologies Inc.] MEDIROM’s mission is to help people lead healthier and happier life with more vitality. Since 2000, MEDIROM has expanded its relaxation salon “Re.Ra.Ku” to 284 stores and the number of single-brand stores in the relaxation business has reached No. 1 in Tokyo, while expanding database marketing based on data collected from our physical condition management app. In 2015, the Institute for Healthcare was established, and in collaboration with doctors and university professors, it has expanded its activities such as research on health promotion and disease prevention in non-disease fields, and coordinated projects specialized in the healthcare field. ■ Overview of MEDIROM Healthcare Technologies Inc. Company name: MEDIROM Healthcare Technologies Inc. Head office location: 3-26-33 Takanawa, Minato-ku, Tokyo, Keikyu Building 10 3F CEO/Founder: Kouji Eguchi, Established: July 2000 Capital: 1,211.2 million yen (including reserves) Business description: Salon management business / franchise business / health tech business URL: <a href="https://medirom.co.jp/en/">https://medirom.co.jp/en/ </a>

MEDIROM Announces Partnership with MATRIX Industries to Deliver The World’s First Health Monitoring Wearable that Never Requires Charging

At the Relaxation Contest JAPAN 2019 held at Hulic Hall Tokyo (Yurakucho Marion 11F, 2-5-1 Yurakucho Marion, Chiyoda-ku, Tokyo) on October 17, 2019, Atsuko Yamada of Re.Ra.Ku Seibu Shinjuku Pepe Store won the Grand Prix in the Therapist category and Re.Ra.Ku Yukari Plaza store won the Grand Prix in the space category. <figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/b9ecca8cdbfd4f71a4994320f51fa69e/575.jpg" alt="" width="400" height="267"><figcaption> </figcaption></figure>【About Relaxation Contest JAPAN】 <figure><img src="https://images.microcms-assets.io/assets/9edf8dbea622483096fe2cacad989656/45e7421945844e0295bf09ffb2b42fef/576.png" alt="" width="240" height="176"><figcaption> </figcaption></figure>This event was sponsored by the Japan Relaxation Industry Association to improve the status of relaxation therapists and to develop the relaxation industry. It is usually held in the second half of October in honor of the Relaxation Day on October 30.  At the 6th relaxation competition that is going to be held in 2019, therapists will compete for hospitality skills to win the prize in the therapist category. On the other hand, each store competing will present their efforts to solve problems that happen in the store, to win in the Space category.Through the contest, we are making various efforts to raise awareness and deepen understanding of the relaxation industry. [Overview of MEDIROM Healthcare Technologies Inc.]Company name: MEDIROM Healthcare Technologies Inc.Headquarters: Keikyu Building 10 3F,3-26-33 Takanawa, Minato-ku, Tokyo, CEO/Founder: Kouji EguchiEstablishment: July 2000Business: Relaxation Salon management business / Franchise business / Health tech business Contacts[Contact details for inquiries]MEDIROM Healthcare Technologies Inc.Public Relations: Daimu NakamuraTel: 81-(0)3-6721-7364Fax: 81-(0)3-6721-7365E-MAIL: press@medirom.co.jp

Relaxation Contest JAPAN 2019 Double Grand Prix

MEDIROM Inc. (headquartered at: Minato-ku, Tokyo; Representative Director: Kouji Eguchi; hereinafter, the “Company”), which consistently supports sectors from health promotion to healthcare through its operation of relaxation salons and development of healthcare IT, has completed a financing of JPY 330 million through a third party allocation of new shares and other issuances, to investors including CCC Marketing Co., Ltd. The Company would like to announce that as a result of this capital raise, stated capital increased to JPY 441.2 million (including capital reserves) on December 30, 2016. The Company carried out this fund-raising effort with eyes toward a planned initial public offering on the New York Stock Exchange. By February 2017, the Company is also expecting to receive additional capital investments overseas to bring the aggregate funds raised, including the funds raised in this round, to JPY 600 million. With this increase in capital, the Company plans to further improve services, expand its business and move toward an expected IPO in the U.S. with a strengthened financial foundation, while also working towards creating a business which instills an even higher level of client trust.

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